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Korean Journal of Otorhinolaryngology-Head and Neck Surgery > Volume 37(3); 1994 > Article
Korean Journal of Otorhinolaryngology-Head and Neck Surgery 1994;37(3): 600-8.
Laryngeal Neuroendocrine Carcinoma
Bong Ki Hong, MD1, Eun Chang Choi, MD1, Kwang-Moon Kim, MD1, Won Pyo Hong, MD1, and Yong Hee Lee, MD2
1;Department of Otorhinolaryngology, 2;Pathology, Yonsei University College of Medicine, Seoul, Korea
후두의 Neuroendocrine Carcinoma
흥봉기1 · 최은창1 · 김광문1 · 홍원표1 · 이용희2
연세대학교 의과대학 이비인후과학교실1;병리학교실2;
ABSTRACT

Neuroendocrine(NE) tumors of the larynx are rare with an estimated incidence of 0.6% of all laryngeal neoplasm and the total number of NE tumor of the larynx reported in the world literature now amounts to about 400 cases. Its diagnostic problems are rarity and submucosal growing. The electron microscopic and immunocytochemical study were necessary for its diagnosis. Wenig(1989) recently adapted Gould's classification of NE neoplasms of the lung to laryngeal tumors and proposed a division of NE carcinomas of the larynx to three groups : well differentiated NE carcinoma, moderately differentiated NE carcinoma, poorly differentiated NE carcinoma. Recently we experienced each case of all 3 subtypes of NE carcinoma, so we report its clinical manifestations and characteristics with a review of literatures.

Keywords: Neuroendocrine tumorsLarynx.
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