As recent development of Immunology and Nuclear medicine, serum IgE and IgG values are helpful in diagnosis and evaluation of therapeutic effect of nasal allergy. Intradermal skin test, provocation test and laboratory tests including eosinophil counts in nasal secretion and blood, and serum Ig E and Ig G values were studied on 75 cases who visited to Allergy Clinic in Han Yang University Hospital. Of these, 43 cases were diagnosed as nasal allergy, and so treated with hyposensitization. The authors have observed changes of serum IgE and IgG levels before and after hyposensitization in the cases in order to assess how valuable these immunoglobulins are as direct evidence of therapeutic effect. So following results were obtained ; 1) Antihistaminics affected nasal allergy during about 4-5 days. So these drugs must be discontinued at least 5 days before test. 2) Sex ratio of male to famale was 1 : 1.4, and the most probable age incidence was 31-40 year-old. Under 20 year-old age, male was predominant and above 21 year-old age, female was predominant. 3) In the group diagnosed as nasal allergy, nasal secretion eosinophilia was observed in 92% and blood eosinophilia was in 44.4%. So nasal secretion eosinophilia was more significant than blood eosinophilia in the diagnosis of nasal allergy. And the relationship between nasal eosinophilia and blood eosinophilia could not be found. 4) 86.7% of the cases showed positive response to intradermal test. Common positive allergens were House dust(66.7%), D. farinae(65.3%), Candida(18.6%) and so on. 5) The provocative ratio to positive skin allergen was 68% for House dust 59.2% for D.farinae, 23.3% for Alternaria and Ragweed. 6) The mean serum Ig E level was 432.8 IU/ml in group A +(group which was demonstrated as allergy), 259.8 IU/ml in group A-(group which not demonstrated as allergy) and 222.1 IU/ml in control group. 7) The mean serum Ig E level of the cases with asthma(517.5 IU/ml) was higher than the level(308.7 IU/ml) of the cases without asthma. 8) The mean serum Ig E level was 402.9 IU/ml in the cases with positive skin test and 180.36 IU/ml in the cases with negetive skin test. So serum Ig E level was correlated with intradermal reaction. 9) The mean serum Ig G level was 1613.0 mg/dl in group A+,1288.6 mg/dl in group A- and 1367.5 mg/dl in control group. 10) After hyposensitization, the size of erythema and the eosinophil in nasal secretion were gradually decreased over time, but these changes were not significant. On the other hand, the provocative reaction was markedly reduced over time after hyposensitization. 11) At 6 months after beginning of hyposensitization, blood eosinophil and serum Ig E levels were slightly decreased and serum Ig G levels were slightly increased. But significant changes were not noted.